Not yet because of AI
Candidates that have not passed the four tests: a drug in Phase III, satellites in orbit, alerts nobody has yet measured a response to. Each one says what would move it onto the main list. These entries carry no grades, because there is nothing to grade yet.
The first generative-AI-discovered drug entered Phase III in September 2026 — no AI-discovered drug has yet been approved anywhere.
What would change this: A positive 52-week FVC result, then regulatory approval, then patients treated outside a trial — each step moves it closer; approval alone does not make it a "because" entry.
Phase III started; 0 approvals
Every Cure's AI ranks 75 million drug–disease pairs; its patient wins so far came from clinicians or predate the window.
What would change this: A documented patient outcome where the drug–disease match originated from the MATRIX platform, with dates.
$76MARPA-H; 10 programs
Three FireSat satellites launched in July 2026 to spot 5×5 m fires from orbit; no fire-response outcome has been measured yet.
What would change this: A documented detection with a timestamp ahead of other systems and a fire-agency response outcome.
3satellites in orbit
Google's urban flash-flood model now gives up to 24 hours' notice worldwide; whether anyone acted on an alert hasn't been measured.
What would change this: An independent impact evaluation (evacuations, losses) tied to specific alerts.
24hflash-flood alerts, global
| Entry | Impact | Attribution | Window | |||||
|---|---|---|---|---|---|---|---|---|
| 1 | The first generative-AI-discovered drug entered Phase III in September 2026 — no AI-discovered drug has yet been approved anywhere. | Phase III started; 0 approvals | Watchlist | not yet | Sep 10, 2026 | — | ||
| 2 | Every Cure's AI ranks 75 million drug–disease pairs; its patient wins so far came from clinicians or predate the window. | $76M ARPA-H; 10 programs | Watchlist | not yet | Feb 26, 2026 | — | ||
| 3 | Three FireSat satellites launched in July 2026 to spot 5×5 m fires from orbit; no fire-response outcome has been measured yet. | 3 satellites in orbit | Watchlist | not yet | Jul 7, 2026 | — | ||
| 4 | Google's urban flash-flood model now gives up to 24 hours' notice worldwide; whether anyone acted on an alert hasn't been measured. | 24h flash-flood alerts, global | Watchlist | not yet | Mar 9, 2026 | — | ||
Nothing matches.